Necrotizing Soft Tissue Infections

Hyperbaric oxygen therapy (HBOT) treating necrotizing soft tissue infections by increasing oxygen levels in affected tissues, promoting bacterial elimination, and supporting faster tissue regeneration.

Treatment of Necrotizing Soft Tissue Infections with Hyperbaric Oxygen Therapy

Necrotizing soft tissue infections (NSTIs) are life-threatening conditions that cause rapid tissue destruction, severe pain, and high mortality if left untreated. These infections often involve deep tissue layers and can result in systemic infection, sepsis, and organ failure. Immediate and aggressive treatment is essential to prevent tissue loss or even death. Hyperbaric Oxygen Therapy (HBOT) has proven to be an effective adjunctive treatment for NSTIs, accelerating healing and reducing the severity of the infection.

HBOT works by delivering pure oxygen in a pressurized chamber, greatly increasing the amount of oxygen that reaches infected tissues. This increased oxygen supply supports the body's immune response by enhancing the activity of white blood cells, promoting angiogenesis (new blood vessel growth), and aiding in the repair of damaged tissues. In the case of NSTIs, where tissue destruction and infection spread rapidly, HBOT can slow the progression of necrosis, improve tissue viability, and support the body's fight against infection. Clinical studies have demonstrated that HBOT, when combined with surgical debridement and antibiotics, can significantly reduce mortality rates, minimize tissue loss, and improve long-term outcomes for patients with NSTIs.

At Hyperbaric Health Services, we offer personalized HBOT treatments to support patients battling necrotizing soft tissue infections. Our team of experts provides care in a safe and controlled environment, ensuring that patients receive the best possible treatment to fight these aggressive infections and promote recovery.

Supporting Evidence

1. Hyperbaric Oxygen Therapy for Necrotizing Soft Tissue Infections

Overview: This guideline from the Undersea and Hyperbaric Medical Society (UHMS) provides detailed recommendations on the use of HBOT as an adjunct therapy for treating necrotizing soft tissue infections. It discusses how increased oxygen delivery to infected tissues can improve outcomes, reduce mortality, and support infection control.
Link: UHMS Guideline on HBOT for NSTIs

2. Hyperbaric Oxygen Therapy as an Adjuvant to Source Control in Necrotizing Soft Tissue Infections

Overview: This article, published in the Undersea and Hyperbaric Medicine Journal, examines the role of HBOT in conjunction with standard surgical debridement and antibiotic treatments. The study highlights how HBOT improves tissue oxygenation, aids in infection control, and reduces the extent of surgical intervention required for NSTIs.
Link: UHMS Journal Article on HBOT for NSTIs

3. Efficacy of Hyperbaric Oxygen Therapy in the Treatment of Necrotizing Soft Tissue Infections

Overview: This PubMed study evaluates the outcomes of HBOT in patients with NSTIs. It discusses how HBOT can reduce the need for extensive surgeries, lower mortality rates, and promote faster recovery by enhancing tissue oxygenation and immune response.
Link: PubMed Article on HBOT for NSTIs

4. Hyperbaric Oxygen Therapy in Necrotizing Fasciitis: A Retrospective Study

Overview: This study focuses on the effectiveness of HBOT in necrotizing fasciitis, a severe form of NSTI. It shows that HBOT, when used alongside surgical debridement and antibiotics, can significantly reduce mortality and improve patient outcomes.
Link: PubMed Study on HBOT for Necrotizing Fasciitis

5. A Multicenter Study on the Role of Hyperbaric Oxygen Therapy in Treating Necrotizing Soft Tissue Infections

Overview: This multicenter study investigates the impact of HBOT on patients with necrotizing infections. It reveals improved survival rates and faster healing in those receiving HBOT as part of their treatment protocol.
Link: PubMed Article on HBOT and Necrotizing Infections

6. The Adjunctive Role of Hyperbaric Oxygen Therapy in Necrotizing Soft Tissue Infections

Overview: This article from PMC reviews the benefits of HBOT as an adjunctive therapy in treating NSTIs. It highlights how HBOT can reduce the progression of tissue necrosis, enhance immune response, and improve overall survival rates.
Link: PMC Article on HBOT for NSTIs